It is purported to reduce the amount of androgens in the body that can convert into estrogen by acting as a suicide inhibitor. Binding to the aromatase enzyme and creating an irreversible reaction.
Word of caution.
This from Patrick Arnold over at Prohormone Forum.com:
"The whole family of 7-oxygenated dhea metabolites are fascinating compounds, for many reasons other than aromatase inhibition. The compound under discussion here is not a major metabolite though, and so its very unlikely you could acheive therapeutic drug levels in your body by ingesting any reasonable amount of 7-keto"
Products containing Arimistane:
PES' NEW Erase Pro
LeCheek Nutrition's AD-3 PCT
Redefine Nutrition (Finaflex) PCT Revolution Black
Ironmaglabs E-Control 2.0
References:Schubert K, Wehrberger K, Hobe G; Androsta-3,5-diene-7,17-dione: isolation from urine and formation from 7-keto-dehydro-epiandrosterone sulphate under various conditions of hydrolysis; Endocrinol Exp. 1971 Dec;5(4):205-10
Numazawa M, Mutsumi A, Tachibana M, Hoshi K; Synthesis of androst-5-en-7-ones and androsta-3,5-dien-7-ones and their related 7-deoxy analogs as conformational and catalytic probes for the active site of aromatase; J Med Chem. 1994 Jul 8;37(14):2198-2
Ashok Marwah, Padma Marwah, Henry Lardy; Ergosteroids VI. Metabolism of dehydroepiandrosterone by rat liver in vitro: a liquid chromatographic–mass spectrometric study. Journal of Chromatography B, 767 (2002) 285–299